摘要
目的探讨颈动脉粥样斑块及内中膜厚度(IMT)与冠心病(CHD)发生的关系。方法对145例疑诊CHD先后作颈动脉超声检查测量IMT和观察粥样斑块及冠状动脉造影。结果非CHD 44例,CHD 101例,IMT为(0.75±0.10)mm和(0.99±0.29)mm;颈部斑块发生率25%(11/44)和77.22%(78/101)。两组比较差异有统计学意义(P<0.005)。硬斑块组发生CHD最高96.55%,软斑块组次之83.33%,无斑块组最低41.07%,各组间比较差异均有统计学意义(P<0.005)。以IMT≥0.85mm或出现斑块来预测CHD,敏感性77.22%,特异性81.81%,阳性预测值83.72%。结论颈动脉粥样斑块及内中膜厚度增加与CHD密切相关,采用颈动脉超声检查可预测CHD发生。
Objective To investigate the relationship between carotid artery plaque,Intimia - media thickness and coronary heart disease. Methods One hundred and forty-five cases of suspected patients with CHD had to do carotid artery ultrasounic examina- tion,observation and measurement of IMT and coronary angiography. Results We found IMT in Non-CHD group and CHD group were 0.75±0.10ram and 0. 99±0.29mm. The prevanlence rate of atherosclerotic plaques were 25% （11/44） and 77.22% （78/ 101） and there were significant difference between the two groups ,P〈0. 005. Hard plaque group CHD highest incidence of 96.55%,followed by soft plaque group was 83.33 % ,the lowest non-plaque group 41.07%. There were significant difference between every two groups,P〈0. 005. An IMT≥0.85mm or the occurrence of atherosclerotic plaques could predict the presence of Coro- nary Heart Disease with a sensitivity of 77.22%, specificity of 81.81%, and a positive predictive value of 83.72%. Conclusion There was close relationship between both carotid atherosclerotic plaque and the increased intimia-media thickness with coronary heart disease. Carotid artery ultrasounic examination could help to predict the incidence of coronary heart disease.
出处
《重庆医学》
CAS
CSCD
北大核心
2009年第13期1606-1607,共2页
Chongqing medicine
关键词
颈动脉斑块
冠心病
超声
冠状动脉造影
carotid artery plaque
coronary heart disease
Coronary angiography
ultrasonography
