摘要
碳酸钾对水杨酸和乙酸酐合成阿司匹林具有良好催化作用。最佳实验条件:水杨酸0.029mol,水杨酸与乙酸酐的物质的量的比为1∶1.75,碳酸钾用量为1.45mmol,反应时间30min,反应温度60℃,产率78.8%。
Potassium carbonate is an excellent catalyst for the synthesis of acetyl salicylic acid from Salicylic acid and acetic anhydride ,the optimum conditions for the reaction were as foilows：The amount of salicylic acid is 0.029mol , The amount of substance ratio of salicylic acid and anthydride acetic is 1：l.75,The amount of Potassium carbonate is 1.45mmol,the reaction time is 30min,the reaction temperature is 60℃, the yield reached 78.8%.
出处
《六盘水师范高等专科学校学报》
2009年第3期22-23,共2页
Journal of Liupanshui Teachers College
关键词
碳酸钾
阿司匹林
合成
potassium carbonate
acetyl salicylic acid
synthesis
