摘要
目的评价外科治疗重症肌无力（MG）的效果，探讨影响术后肌无力危象发生及治疗效果的因素。方法回顾我院2000-2007年外科治疗21例重症肌无力患者的临床资料，对其疗效及影响术后肌无力危象发生及影响治疗效果的因素进行分析。结果重症肌无力的症状完全缓解有5例（23.8％）部分缓解14例（66.7％）无效1例（4.8％），死亡1例（4.8％）。病程长短、Osserman分型和胸腺的病理类型是术后肌无力危象发生的相关危险因素，治疗效果与病程、Osserman临床分型有关。结论外科治疗重症肌无力有良好的效果及可行性。
Objective To evaluate the effectiveness of thymectomy for myasthenia gravis （MG）and the relative factors for postoperative myasthenic crisis and the treatment outcome of thymectomy. Methods The clinic data of 21 cases with MG who underwent thymectomy from 2000 to 2007 to analyse the relative factors for postoperative myasthenic crisis and the treatment out-come of myasthenia gravis treated with thymectomy. Results The symptom of MG was complete remission in 3 cases（14.3%）, partial remission in 14 cases （66.7%）,unchanged in 3 cases （14.3%）,and 1 case （4.8%） was dead 3 years after thymectomy. The symptom duration before operation, Osserman stage and pathological type of thymoma were relative risk factors for postoperative myasthenic crisis. And the symptom duration before operation, Osserman stage were relative factors for the treatment out-come of thymectomy. Conclusion Surgical treatment shows significant clinical benefits for patients with MG.
出处
《四川医学》
CAS
2009年第6期925-927,共3页
Sichuan Medical Journal
