摘要
目的探讨胰岛素强化治疗初诊2型糖尿病的最佳方案。方法将38例初诊的2型糖尿病随机分组为A组甘精胰岛素组(19例),B组中性鱼精蛋白锌胰岛素组NPH(19例),分别三餐前联用门冬胰岛素,观察两组病人治疗前后各项临床指标变化。结果两组治疗方案均能较好的控制血糖,甘精胰岛素组血糖达标时间、低血糖发生率、胰岛素总量低于NPH组(P<0.01)。结论甘精胰岛素联合门冬胰岛素是初诊2型糖尿病强化治疗的首选方案。
Objective To investigate the most effective intensive insulin therapy for newly diagnosed type 2 diabetes（T2DM）.Methods 38cases patients with newly-diagnosed T2DM were randomized into two groups： group A （n=19）,Aspart supplied before meals and Glargine at bedtime, group B （n=19）,Aspart supplied before meals and NPH at bedtime.The changes of some clinical indexes in each group were observed before and after treatment. Results Both groups can effectively control blood glucose,but the good effective time, bad effects and insulin dosage in group A were less than group B （P〈0.01）. Conclusion Aspart supplied before meals and Glargine at bedtime might be the first choice for patients with newly-diagnosed T2DM in intensive insulin therapy.
出处
《医学信息》
2009年第7期1304-1306,共3页
Journal of Medical Information
