摘要
近年来研究表明,肿瘤抑制基因PTEN不仅与脑发育和分化调控密切相关,而且其介导的信号网络还广泛参与了缺血性脑损伤的病理生理过程。深入研究PTEN在缺血性脑损伤中的分子调控机制将为缺血性脑损伤的治疗提供新的思路。
Recent studies have revealed that tumor suppressor PTEN does not only closely relate to the development and differentiation of brain but also get extensively involved into the pathophysiological processes of ischemic brain injury. Through research on the mechanisms of molecular regulation mediated by PTEN in ischemic brain injury will provide new perspectives for the treatment of ischemic brain injury.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2009年第11期867-868,共2页
Journal of Applied Clinical Pediatrics
基金
国家自然科学基金项目资助(30770748)
关键词
肿瘤抑制基因
脑损伤
缺血
tumor suppressor
brain injury
ischemia
