摘要
目的:评估灰阶超声造影在诊断乳腺良恶性病变中的价值。方法:应用超声造影观察61例患者的62个乳腺病灶,评估其病灶内部的灌注特征。结果:62个病灶经病理检查证实为恶性病灶共32个,良性病灶30个。与良性病灶相比,恶性病灶较容易出现灌注缺损和灌注不均(P值分别为0.002、0.010)。病灶内部出现灌注缺损诊断乳腺恶性病变的灵敏度为71.9%(25/32),特异度为66.7%(20/30),准确率为69.4%(43/62);灌注不均诊断恶性病变的灵敏度、特异度和准确率分别为78.1%(25/32)、53.3%(16/30)和66.1%(41/62)。结论:超声造影是诊断和鉴别乳腺良、恶性病变的有效手段。
Objective To evaluate the use of gray scale contrast-enhanced ultrasound in the differential diagnosis of benign and malignant breast lesions. Methods Sixty-two breast lesions in 61 patients were assessed by gray scale contrast-enhanced ultrasound after injection of the contrast agent SonoVue. Contrast-enhancement patterns of breast lesions were analyzed. Results Histopathologic examination revealed that 32 lesions were malignant and 30 were benign. On contrast-enhanced ultrasound, focal enhancement defects were largely associated with malignant tumors （P=0.002） and had a sensitivity of 71.9%（23/32）, specificity of 66.7% （20/30） and accuracy of 69.4% （43/62）. Similarly, the frequency of heterogeneous enhancement was higher in malignant lesions than that in benign lesions （P=0.010） and the sensitivity for heterogeneous enhancement was 78.1% （25/32）, specificity was 53.3% （16/30）, and accuracy was 66.1% （41/62）. Conclusions Gray scale contrast-enhanced ultrasound may be a useful method for differentiating benign from malignant breast lesions.
出处
《诊断学理论与实践》
2009年第3期322-324,共3页
Journal of Diagnostics Concepts & Practice
关键词
乳腺病变
超声检查
鉴别诊断
Breast lesions
Uhrasonography
Differential diagnosis
