摘要
目的探讨阻塞性睡眠呼吸暂停对老年卒中患者认知功能障碍的影响及其发病机制。方法确诊脑卒中患者配带手握式脉博血氧监测仪,确诊OSAS和并脑卒中患者48例,未患OSAS的脑卒中患者56例,作为对照组。进行身高、体质量测量;收集晨起空腹血标本,进行血浆黏度、纤维蛋白原、血糖及血脂、血压的测定;进行临床记忆量表检测。结果SAS组与对照组平均动脉压、血脂、血糖、血浆黏度、纤维蛋白原比较差异有统计学意义,SAS组与对照组指向记忆、联想记忆、无意义图形再认、记忆商等指标比较差异有统计学意义。结论OSAS可以加重卒中患者的认知功能障碍,并探讨其发病机制。
Objective To analyze the obstructive sleep apnea syndrome （OSAS） with cerebrovascular disease older cognitive dysfunctions and exploring its mechanisms. Methods 48 patients with OSAS were diagnosed by PSG. And 56 patients is a control group was established. They all have cerebrovascular disease. And whole blood plasma fibrinogen（Fng）,blood sugar,blood fat and blood pressure were observed. Tow group were examined by clinical memory test. Results The levels of plasma Fng,blood sugar,blood fat and blood pressure in OSAS group were obviously higher than those in control group （P〈0.05）,Memory quotient（MQ） in OSAS group were lower than those in the control group （P〈0.05）. Conclusion The OSAS patients have cognitive dysfunctions and exploring its mechanisms
出处
《中国老年保健医学》
2009年第2期14-15,共2页
Chinese Journal of Geriatric Care
基金
天津医科大学基金资助项目(2006KY30)
关键词
睡眠呼吸暂停综合征
脑卒中
认知障碍
老年
Sleep apnea syndrome,cerebrovascular disease,cognitive dysfunctions,older
