摘要
目的探讨卵巢上皮癌手术中腹膜后淋巴结清扫的临床价值。方法对389例卵巢上皮癌患者进行回顾性研究,Log-rank test进行差异性检验,Cox风险比例模型进行预后多因素回归分析。结果早期卵巢上皮癌行腹膜后淋巴结清扫并不能提高生存率(P>0.05),晚期卵巢上皮癌行腹膜后淋巴结清扫能提高患者的生存率(P<0.05);卵巢上皮癌腹膜后淋巴结清扫组中残余灶<2 cm的生存率高于残余灶≥2 cm的患者(P<0.05)。多因素分析显示,临床期别、残余灶、腹膜后淋巴结清扫和化疗疗程是卵巢上皮癌的独立预后因素。结论虽然腹膜后淋巴结清扫可以改善卵巢癌患者生存率,但是建议有选择的进行;对残余灶≥2 cm的卵巢上皮癌患者,行腹膜后淋巴结清扫是没有意义的。
Objective To study the value of retroperitoneal lymph node dissection in the treatment of epithelial ovarian cancer. Methods 389 cases of epithelial ovarian cancer were studied retrospectively. Log-rank test was used to conduct differential test, Cox proportional hazard models were given multi-factor prognostic regression analysis （ P 〉 0. 05 ）. Results Early ovarian cancer retroperitoneal lymph node dissection can not improve the survival rate （P 〉 0. 05 ） , the advanced epithelial ovarian cancer retroperitoneal lymph node dissection can increase the survival rate （P 〈 0. 05 ）. The survival rate of epithelial ovarian cancer retroperitoneal lymph node dissection group with residual lesions smaller than 2 cm was higher than that of residual lesions greater than or equal to 2 cm patients （P 〈0.05）. Multivariate analysis showed that clinical stage, residual lesions, retroperitoneal lymph node dissection and chemotherapy treatment of epithelial ovarian cancer were independent prognostic factors. Conclusion Retroperitoneal lymph node dissection can improve survival rate of patients with ovarian caneer,but it is advised to have a choice. For the residual lesions greater than or equal to 2 cm in patients with epithelial ovarian cancer, the retroperitoneal lymph node dissection is meaningless.
出处
《滨州医学院学报》
2009年第3期195-197,共3页
Journal of Binzhou Medical University
关键词
卵巢上皮癌
腹膜后淋巴结清扫
epithelial ovarian cancer,retroperitoneal lymph node dissection
