摘要
目的比较肝癌射频消融术与手术切除治疗的临床效果。方法通过计算机检索和手工检索全面收集关于射频消融术与手术切除治疗肝癌的临床对照研究文献,并按Cochrane协作网推荐的方法进行Meta分析。采用固定效应模型,对符合纳入标准的6个实验共736例病人进行Meta分析。结果与手术组相比,射频消融组的术后3年生存率低,差异有显著性[RR=1.25,95%CI=(1.00,1.57),P<0.05]。结论应用射频消融术治疗肝癌3年后病人死亡的相对危险度是手术切除的1.25倍,手术切除术治疗肝癌疗效优于射频消融术。
Objective To compare the therapeutic effects of radiofrequency ablation versus hepetectomy for liver cancer. Methods Clinical data of patients with liver cancer underwent radiofrequency ablation or hepatectomy were collected from literature via electronic searching and handwork-searching. Meta-analysis that recommended by Cochrane Collaboration was done for the data obtained, 736 patients who met the six criteria of enrollment were included in this study using fixed-effect model. Results Compared with that of surgery, three year survival in those underwent radiofrequency ablation was statistically lower [RR 1.25, 95 % CI= （1.00,1.57）,P〈0.05]. Conclusion Applying radiofrequency ablation, the relative risk of death after three years of therapy is higher than surgical resection. The therapeutic outcome of surgery is better than the ablation.
出处
《齐鲁医学杂志》
2009年第5期413-415,共3页
Medical Journal of Qilu
基金
青岛市卫生局医药学科科研项目(2004-wsxk003)
关键词
肝肿瘤
导管消融术
外科手术
META分析
Liver neoplasms
Catheter ablation
Surgical procedures
Meta analysis
