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热熔压敏胶在中药透皮吸收制剂中的研究进展 被引量:11

Application of thermoplastic elastomer in hot-melt pressure sensitive adhesives for transtermal drug delivery
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摘要 药物制剂的发展很大程度上依赖于药用辅料的发展,一种新型高分子药用辅料的开发将带动一类药物新剂型和一大批药物新制剂的发展。热塑性弹性体是一种新型的高分子药用辅料,目前在热熔压敏胶领域应用广阔。本研究主要综述了一种新型中药透皮吸收制剂——热塑性弹性体热熔压敏胶,对热塑性弹性体及其改良进行了介绍,并就热熔压敏胶在中药透皮制剂中的发展应用进行了展望,认为热塑性弹性体热熔压敏胶在中药透皮吸收制剂领域具有广阔的发展前景。 Development of drug dosage forms to a great extent depends on the development of drug auxiliary materials. Tlae development of a new type of polymeric drug auxiliary materials will bring on the developing of a novel dosage forms technology and a flood of new drug dosage forms. Thermoplastic elastomer is a new type of drug polymeric auxiliary materials, at present, which has a broad application in the field of hot-melt pressure sensitive adhesives. This review mainly discussed a new transtermal Chinese drug delivery system, including matrix composition of the formula, modified thermoplastic elastomer for hot-inch pressure sensitive adhesives and their development prospects in the traditional Chinese drug delivery system. It suggested that thermoplastic elastomer of hot-meh pressure sensitive adhesives has broad development prospects in the field of the transtermal drug delivery system for traditional Chinese medicine.
出处 《中国中药杂志》 CAS CSCD 北大核心 2009年第12期1612-1614,共3页 China Journal of Chinese Materia Medica
基金 中医外治特色疗法和外治技术示范研究项目(2008BAI53B076)
关键词 热塑性弹性体 热熔压敏胶 HMPSA 中药透皮吸收制剂 基质配方 SIS SBS thermoplastic elastomer hot-meh pressure sensitive adhesives HMPSA transtermal Chinese drug delivery system matrix composition SIS SBS
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