摘要
目的探讨骨密度水平与不同类型颈动脉粥样硬化斑块之间的关系。方法选取164例经超声检查证实颈动脉粥样硬化斑块形成患者,根据超声特征分为软斑块组、混合斑块组和钙化斑块组;另取50例同期行超声检查未发现颈动脉粥样硬化斑块患者为对照组,测定骨密度水平。结果年龄、收缩压、脉压差、总胆固醇、低密度脂蛋白、空腹血糖是颈动脉粥样斑块发生的危险因素;骨密度降低与颈动脉钙化斑块发生之间密切相关,而与颈动脉混合斑块及软斑块发生无相关。结论骨密度水平降低是颈动脉钙化斑块发生的独立危险因素。
Objective To investigate the relationship between bone mineral density and different types of carotid atherosclerotic plaque. Methods One hundred and sixty -four patients who were diagnosed with carotid atherosclerotic plaque by uhrasonography were selected, and then, according to the results of Doppler ultrasound, they were assigned to three groups： soft, fibrous, and largely calcified groups. At the same time, fifty patients who were not diagnosed with carotid atherosderotic plaque by ultrasonography were selected as control group. Determination of the bone mineral density degree of ankle was conducted in all of the subjects by using the USA Norland Dove SXA - 3000 Bone Density Meter. Results Partial correlation analysis revealed that age, systolic pressure, pulse pressure, total cholesterol, low - density lipoprotein cholesterol and fasting plasma sugar were closely correlated with the formation of carotid atherosclerotic plaque. Also, loss of bone mineral density was found to be closely correlated with the incidence of carotid calcified plaque and not correlated with the incidence of carotid soft plaque and fibrous. Conclusion This study hints that loss of bone mineral density was an independent risk factor of the incidence of carotid calcified plaque.
出处
《中国预防医学杂志》
CAS
2009年第6期472-474,共3页
Chinese Preventive Medicine
关键词
骨密度
颈动脉
粥样硬化斑块
Bone mineral density
Carotis
Atherosclerotie plaque
