摘要
目的：研究半夏泻心口服液对实验性慢性胃炎的作用机理。方法：以半夏泻心口服液对乙醇及脱氧胆酸钠诱发的实验性慢性胃炎大鼠进行治疗，疗程结束后用放免法检测大鼠血浆ＴＸＢ２和６－Ｋｅｔｏ－ＰＧＦ１ɑ水平。结果：半夏泻心口服液能显著降低血浆ＴＸＢ２和６－Ｋｅｔｏ－ＰＧＦ１ɑ，两者比值亦下降。结论：半夏泻心口服液治疗慢性胃炎的机制可能与调整ＴＸＢ２和６－Ｋｅｔｏ－ＰＧＦ１ɑ的动态平衡，改善胃粘膜微循环，增加胃粘膜氧、能供应有关。
Abstract\ Objective:To study the mechanism of Rhizoma Pinelliae Fluid for Reducing Stomach Fire (Ban Xia Xie Xin Kou Fu Ye)on chronic gastritis in laboratory.Methods:Rhizoma Pinelliae fluid for Reducing Stomach Fire Was given to rats with chronic gastritis induced by alcohol and sodium deoxycholate.After treatment,the levels of plasma TXB2 and 6KetoPGE1α were determined with radioimmunoassay.Results:Rhizoma Pinelliae Fluid for Reducing Stomach Fire significangly reduced the levels of plasma TXB2 and 6KetoPGF1α and their ratio as well.Conclusion:The therapeutic effect of chronic gastritis by Rhizoma Pinelliae Fluid for Reducing Stomach Fire may result from the promotion of blood flow in gastric mucosa and from the increase of the supply of oxygen and energy to gastric mucosa. \ \ KEY WORDS:Rizoma Pinelliae Fluid for Reducing Stomach Fire,chronic gastritis,TXB2,6KetoPGF1α
出处
《南京中医药大学学报》
CAS
CSCD
1998年第4期220-221,共2页
Journal of Nanjing University of Traditional Chinese Medicine
