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不同剂量率的紫外线对红细胞及其膜的影响 被引量:1

EFFECT OF DOSE RATE ON UV-IRRADIATION INDUCED DAMAGE TO ERYTHROCYTE AND ERYTHROCYTE MEMBRANE
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摘要 用剂量率分别为2.22、3.33、4.44和8.88mW/cm2的紫外线照射由新鲜猪血制备的红细胞和红细胞膜,通过检测红细胞的溶血度及红细胞、红细胞膜的过氧化程度来研究射线所致的辐射损伤。结果表明,同一剂量下,经较低剂量率照射的红细胞溶血度较大,且受放置时间的影响很小,被辐射红细胞和红细胞膜的过氧化产物丙二醛(MDA)的量也显示反剂量率效应。 Erythrocyte and erythrocyte membrane made from fresh pig blood were irradiated with UV at dose-rates of 2.22, 3.33, 4.44, 8.88mW/cm^2, respectively, and the radiation induced hemolysis and peroxidation were measured in order to investigate the influence of the dose-rate of UV on radiation-induced membrane damage. The results indicated, at the same dose, the hemolysis of erythroeyte in the low dose rate radiation were larger, and little sufferd by laying time. The peroxidation products of irradiated erythrocyte and erythroeyte membrane also showed an inverse dose-rate effect.
出处 《核农学报》 CAS CSCD 北大核心 2009年第3期526-529,共4页 Journal of Nuclear Agricultural Sciences
基金 国家自然科学基金项目(10505018)
关键词 紫外辐射 红细胞 红细胞膜 剂量率 UV-radiation erythrocyte erythrocyte membrane dose-rate
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