摘要
目的研究老年社区获得性肺炎患者病原体分布,为其经验治疗提供依据。方法入选2005年5月-2008年4月医院干部呼吸内科的204例社区获得性肺炎患者,进行病原体检测,并按CURB-65评分系统评分。结果在204例患者中,检出病原体151株,肺炎支原体是最常见的病原体,阳性率为20.6%,其后依次为肺炎链球菌、流感嗜血菌、肺炎克雷伯菌、肺炎衣原体、大肠埃希菌、铜绿假单胞菌、白色假丝酵母菌、金黄色葡萄球菌、嗜肺军团菌、鲍氏不动杆菌,分别占19.9%、15.9%、11.3%、9.3%、4.6%、3.3%、3.3%、2.6%、1.3%、0.7%;混合感染患者的CURB-65评分高于单一感染患者。结论老年社区获得性肺炎非典型病原体的感染占重要地位,革兰阴性杆菌、金黄色葡萄球菌及真菌的感染多见,混合感染不容忽视。
OBJECTIVE To investigate the pathogenic causes of community acquired pneumonia（CAP） in the elderly and to guide experience antibiotic therapy. METHODS An etiological study was performed on 204 elder patients with CAP in the Cadres Medical Department of Beijing Shijitan Hospital from May 2005 to Apr 2008. The count scores were by CURB-65 scoring system. RESULTS Pathogens were identified in 204 patients： there were Mycoplasma pneumoniae （42, 20. 6 %）, Streptococcus pneumoniae （30, 14. 7 %）, Haemophilus in f luenzae （24,11. 8 %）, Chlamydia pneumoniae （ 17,8. 3 %）, Klebsiella pneumoniae （ 14,6. 9 %）, Escherichia coli （7,3. 4 %）, Pseudomonas aeruginosa （5,2.5 % ）, Staphylococcus aureus （4,2. 0 % ） , Legionella pneumophila （2,1. 0 % ）, and Acinetobacter baumannii （1,0. 5 %）. The score, by CURB-65 scoring system, of mixed infected patients was higher than single infections. CONCLUSIONS Atypical pathogens have important role in elderly CAP, the most common pathogenare Gram-negative bacilli, S. aureusand fungi. Mixed infection couldn＇t be ignored.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第12期1509-1511,共3页
Chinese Journal of Nosocomiology
关键词
老年患者
社区获得性肺炎
病原体
Elderly patient
Community acquired pheumonia
Pathogens
