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肥大细胞在小鼠子宫的分布及其在动情周期中变化的定量研究 被引量:14

CHANGES IN UTERINE MAST CELL COUNT DURING THE ESTROUS CYCLE IN THE MICE
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摘要 本研究用动情前期、动情期、动情后期、动情间期雌性小鼠各5只。取子宫,入4%中性甲醛固定,做石蜡切片,用pH0.5的0.5%甲苯胺蓝染色。对动情周期各期子宫壁内的肥大细胞进行观察和计数,并用方差分析法检验各期肥大细胞数量差异的显著性。结果表明,小鼠子宫肥大细胞主要分布在子宫肌层,在子宫内膜极少。肥大细胞数量,随动情周期有所变化。在动情后期数量最多,在动情前期数量最少,二者之间差异有高度显著性(P<0.01)。动情前期分别同动情间期和动情期比较,也都有显著的差异(P<0.05)。本文对小鼠动情周期子宫肥大细胞数量变化的机制进行了讨论。 Adult virgin female mice were killed at each stage of the estrous cycle. The mid pieces of uteri were taken and fixed in 4% neutral formaldehyde, and stained with 0.5% toluidine blue at pH 0.5. It was found that mast cells in uterus were mainly distributed in the myometrium, only a few in the endometrium. The mast cell number was maximum in metestrus and minimum in proestrus, and this difference was highly significant (P<0.01), The difference between the mast cell number in proestrus and those in estrus and diestrus was also significant(P<0.05). These findings indicate that uterine mast cell number varied in estrous cycle in mice.
作者 景雅 何泽涌
出处 《解剖学报》 CAS CSCD 北大核心 1990年第3期312-314,共3页 Acta Anatomica Sinica
关键词 肥大细胞 子宫 动情周期 细胞计数 Mast cell Cell count Estrous cycle Uterus Mouse
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