摘要
以消旋丙交酯、左旋丙交酯和乙交酯为原料,以辛酸亚锡为引发剂,在高真空条件下本体熔融开环聚合,制得一系列不同旋光度的丙交酯乙交酯共聚物(PLGA),其结构经1H NMR,IR,XRD和DSC表征。并采用DSC研究了PLGA的熔体结晶行为,结果表明其结晶性能随其旋光度的减少而显著降低,甚至不结晶。
A series of poly （lactide-co-glycolide） （PLGA） with different optical rotation were prepared from glycolide, DL-lactide and L-lactide by ring-opening copolymerization in noumenon molten state using stannous octoate as an initiator under high vacuum. The structures were characterized by ^1H NMR, IR, XRD and DSC. The melt-crystalhzation behavior of PLGA has been investigated by DSC. The results show that as the optical rotation of PLGA decreases, their crystaUizability decreases significantly, even when no crystallize has occurred.
出处
《合成化学》
CAS
CSCD
北大核心
2009年第3期292-295,共4页
Chinese Journal of Synthetic Chemistry
关键词
丙交酯
乙交酯
共聚物
熔融聚合
lactide
glycolide
copolymer
molten state copolymerization
