摘要
目的研究不同剂量食用合成色素苋菜红和日落黄诱导蚕豆根尖微核率的变化。方法采用蚕豆根尖微核试验检验2种合成色素在其允许最大使用量的2、1、1/2、1/4、1/8和1/16倍剂量下对根尖细胞微核率的影响。结果苋菜红和日落黄分别在3.125～100和6.25～200 mg/L剂量范围内诱导蚕豆根尖的微核率明显升高。结论苋菜红和日落黄对蚕豆根尖细胞有一定的遗传毒性。
[ Objective ] To study the micronucleus rate induced by Amaranth and Sunset Yellow in roottip cells of Vicia faba. [ Methods ] Micronucleus test was applied to assay the effect of Amaranth and Sunset Yellow at the doses about 2, 1, 1/2,1/4,1/8, 1/16 times of the acceptable maximum level on micronucleus rates of root tip cells of Vicia faba, respectively. [ Results] The micronucleus rates of Vicia faba increased at the dose range of 3. 125 - 100 mg/L in Amaranth and of 6.25 - 200 mg/L in Sunset Yellow. [ Conclusion ] Amaranth and Sunset Yellow have a certain degree of genetic toxicity on Vicia faba root tip ceils.
出处
《职业与健康》
CAS
2009年第12期1240-1242,共3页
Occupation and Health
基金
广东省科技计划项目(2003C20419)
广东检验检疫局科技项目(GDK04-2004)资助
关键词
日落黄
苋菜红
蚕豆根尖
微核
Sunset yellow
Amaranth
Root tip of Vicia faba
Micronucleus
