摘要
目的:探讨重症急性胰腺炎(SAP)继发感染的临床特点。方法:将我院2003.9~2005.3收治的SAP140例,按是否感染,分成感染组和对照组,对比分析其临床资料。结果:感染组病死率高于对照组(P=0.023);感染组入院初期,Ranson评分、CT评分、APACHEⅡ评分、血糖、ARDS和肠麻痹发生率、感染前手术率及呼吸机辅助呼吸率高于对照组(P<0.05);以G-感染胰腺、胰周围及肺部为主;肺部感染时间为10.7±2.5d,胰腺或胰周为17.6±2.9d。结论:急性期全身反应轻重及胰腺坏死程度是SAP继发感染的基础;临床有创治疗措施是促进因素。
Objective: To investigate clinical characteristics of severe acute panereatitis (SAP) complicated with infection. Methods: One hundred and forty SAP treated in our hospital from September, 2003 to March, 2005 were divided into 2 groups: infection group and control group. The clinical data were analyzed. Results: The mortality in the infection group were higher than those in the control group(P〈0. 05). In the early days of hospitalization, the Ranson scores, CT scores, A-PACHEH scores, serum glucose, incidences of acute respirstory distress syndrome and enteroplegia, operability, rates of assisted respiration were higher in infection group than those in control group. Most of the infected cases were oceured in pancreas or peripanereas and lung, while the main infectors were G-bacteria. The incidence time of pulmonary infection and the pancreatic or peripanereatic infection were 10.7±2.5 days and 17.6±2.9 days respectively. Conclusion: The degree of systemic response and necrosis are the base of SAP complicated with infection and any vulnerarious therapeutic measure is its promoting factor.
出处
《华西医学》
CAS
2009年第5期1137-1139,共3页
West China Medical Journal
基金
四川省中医药管理局专项基金(No.2007B03)
四川省人事厅省学科带头人培养基金(No.07SRC-13)
关键词
重症急性胰腺炎
感染
多脏器功能衰竭
severe acute pancreatitis (SAP)
infection
clinical investigation