摘要
目的:探讨ICU机械通气患者使用脑电双频指数(BIS)指导镇静的临床作用。方法:采用前瞻性完全随机对照研究。将53例患者分为2组,分别用BIS和主观评分进行镇静监测48h,设定SAS评分3～4分为镇静目标,评估临床指标如机械通气时间、ICU住院日、给药率和肢体制动率的组间差异,评价BIS监测在机械通气患者的临床应用价值。结果:两组患者均达镇静目标,BIS监测较常规镇静监测组机械通气时间(17.33±15.77dvs.39.83±56.33d)和ICU住院日(21.60±20.45dvs.41.67±55.81d)缩短,肢体制动率下降(40.70%vs.76.90%)(P<0.05),但给药率无统计学意义(P>0.05)。结论:BIS监测可以缩短ICU患者的机械通气时间和GICU住院日,减少肢体制动率。
Objective： To investigate the effects of sedation guided by bispectral index monitor （BIS） in ventilated patients in general intensive care unit （ICU）. Methods： Fifty-three ventilated patients in ICU were randomly assigned to BIS group in which the sedation was guided by BIS continuously for forty-eight hours or controlled group in which the sedation was guided by subjectively SAS grading. The sedation goal was SAS score to be three to four. To compare the ventilated time, ICU days, rate of dosage-used and rate of body brake between the two groups. Results： All patients reached the the sedation goal. Compared with the controlled group the ventilated time, ICU days and rate of body brake were less in BIS group significantly （P〈0.05）. No significant difference was observed in the rate of dosage-used between the two groups. Conclusion： BIS can shorten the ventilated patients＇ ventilated time and ICU days, also can reduce the rate of body-brake of ventilated patients in ICU.
出处
《华西医学》
CAS
2009年第5期1133-1135,共3页
West China Medical Journal
基金
成都市科学技术局2007年攻关计划重点资助项目(成科计[2007]1号)
