摘要
目的:了解广东省监狱系统在押HIV/AIDS犯人的细胞免疫状况,为临床防治AIDS提供参考。方法:应用流式细胞仪对436例广东省监狱系统的在押的HIV/AIDS患者进行CD4+T细胞计数,并定期监测。结果与结论:436例中的感染者CD4+T细胞计数结果少于200μ/L者占24.5%,200~350μ/L者占26.6%,超过350μ/L者占48.9%。不同年龄组之间CD4+T细胞计数存在差异,25岁以后随着年龄增长,CD4+T细胞计数呈下降趋势。未经治疗的201例患者3个月后CD4+T细胞计数较首次检测明显下降,而经治疗的20例则明显增加。提示应对HIV/AIDS患者的CD4+T细胞计数进行检测及定期监测,以了解其免疫状态的变化,并应予积极的抗病毒治疗以改善其免疫状况。
Objective： To investigate the cell immune status of prisoners with of Guangdong province for offering reference to prevention and treatment HIV/AIDS, analysis were used for CD4^＋ T lymphocyte counts in 436 prisoners with HIV/AIDS in HIV/AIDS in prison system Methods： Flow cytometry prison system of Guangdong province. Results and Conclusion： 24. 5% of 436 HIV positive prisoners had CD4^＋ T lymphocyte counts lower than 200/μL, 26. 6% from 200/μL to 349/p,L, and 48.9% more than 350/p,L. The CD4^＋ T lymphocyte count had significant difference among different age groups, and the CD4^＋T lymphocyte counts in patients over 25 years old trended to decrease with increasing age. Compared to the first test results, the CD4^＋T lymphocyte counts of 201 cases without therapy obviously decreased after 3 months, CD4^＋ T lymphocyte counts of 20 cases with therapy obviously increased inversely. It shows that CD4 ^＋ T lymphocyte counts of HIV/AIDS patients should be detected and followed periodically to comprehend the change of their immune status, and antiviral therapy should be offered energetically to improve their immune status.
出处
《新医学》
2009年第6期366-368,共3页
Journal of New Medicine
基金
广东省医学科学技术研究基金资助项目(2006A077)
