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甲状腺球蛋白抗体、甲状腺微粒体抗体不同条件下在血清中的稳定性

Thyroglobulin antibody(TGAb),thyroid microsomal antibodies(TMAb) under different conditions in the stability of the serum
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摘要 目的探讨甲状腺球蛋白抗体(TGAb)和甲状腺微粒体抗体(TMAb)不同条件下在血清中的稳定性。方法用放射免疫法测定放置室温、4℃冰箱、冰冻条件下,不同时间段血清样本中的TGAb与TMAb的活性。结果3种条件在储存2 d以后的结果差异无统计学意义;储存4 d后,室温条件下样品的TGAb与TMAb失活;储存6 d后,4℃冰箱条件下样品的TGAb与TMAb失活;储存29 d后,冰冻条件下样品的TGAb与TMAb失活。结论使用4℃冰箱保存4 d内的血样进一步作甲状腺抗体的检测,可以保证其准确性且又不影响日常临床工作。 Objective To investigate the thyroglobulin antibody (TGAb) and thyroid microsomal antibodies (TMAb) under different conditions in the serum Stability. Methods Measured by radioimmunoassay place at room temperature, 4 ℃ refrigerator, ice conditions, the different time periods in serum samples of TGAb and TMAb activity. Results Three conditions in the storage Two days later the results of no significant difference; stored 4 days at room temperature samples TGAh and TMAb inactivation; storage 6 days, 4℃ refrigerator under the conditions of the samples TGAb and TMAb inactivation; store 29 days later, the frozen samples under the conditions of TGAb and TMAb inactivation. Conclusion 4℃ refrigerator used to preserve blood samples for further screening for thyroid antibodies, the most suitable for day-to-day clinical work.
作者 郭永铁
出处 《国际检验医学杂志》 CAS 2009年第5期465-466,共2页 International Journal of Laboratory Medicine
关键词 甲状腺球蛋白 抗体 微粒体 Thyroglobulin Antibodies Microsomes
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