摘要
观察尿激酶(UK)溶栓治疗超早期脑梗塞的疗效、安全性,探讨其用药剂量、方法、适应症;及溶栓前后血浆D-二聚体的变化。方法:对起病<6小时,或起病超过6小时,小于12小时,CT阴性的20例脑梗塞患者,采用静脉快速滴注UK30万单位,视临床症状的演变,可追加UK剂量,总剂量不超过200万单位;并对治疗前后患者的神经功能缺损进行评定,检测治疗前后血浆D-二聚体的水平。结果:UK应用后患者的临床症状明显改善,患者的平均住院日下降,血浆D-二聚体明显升高(P<0.01)。结论:UK溶栓治疗超早期脑梗塞具有疗效高、安全的特点。
To observe the curative effect, safety, dosage, method of Thrombolytic therapy in the ultra early cerebral infarction, and alteration of D-dimer concentrations. Method: 20 cases suffered form cerebeal infarction by CT scan, <6 hour or >6 hour and <12 hour after the onset of ischemic stroke, useing urokinase (UK) by 300 thousand unit intravenous injection. Total dosage is <2000 thousand unit. After treatment, the scale of neurological deficit was used for functional assessment; Plasma fibrin D-imer levels was measured. Results; Patiants obtain improvement dramatically, average days in - hospitaled is decline, and the D - dimer levels significant in creases after UK treatment (P<0. 001). Conclusion: Thrombolytic therapy of useing UK in the early cerbral infarqtion is positive effect and safety.
出处
《脑与神经疾病杂志》
1998年第3期142-144,共3页
Journal of Brain and Nervous Diseases
关键词
尿激酶
脑梗塞
溶栓疗法
治疗
Urokinase (UK) cerebral infarction (Ischemic Stroke) Thrombolytic therapy
