期刊文献+

脑胶质肉瘤的诊断和治疗(附14例报道) 被引量:3

下载PDF
导出
摘要 目的探讨胶质肉瘤的诊断与治疗方法,以提高对本病的认识。方法回顾性分析我们从2002年7月至2006年10月收治的14例经病理证实的胶质肉瘤病例的临床资料。结果男10例,女4例,年龄15~71岁,平均44.6岁,患者主要表现为头痛,呕吐等颅内高压症状,发病时间为20~40 d,MR显示肿瘤均呈不规则团块状异常信号,其中10例合并明显的厚壁环形强化,形态不规则呈分叶状,并可见不规则的强化壁结节。3例肿瘤次全切除的患者平均生存时间为6.7个月短于7例1次肿瘤全切除患者的11.9个月,其中3例术后综合进行了系统的X刀-放疗和化疗,平均生存时间为13.5个月。另外4例患者接受了两次肿瘤全切除手术和系统的放化疗,平均生存时间延长为18.5个月。结论迅速恶化的病情和MR表现有助于胶质肉瘤的术前诊断,确诊仍需要组织病理学支持;手术全切除肿瘤结合术后的放化疗为其目前较好的治疗方法。
出处 《中国神经精神疾病杂志》 CAS CSCD 北大核心 2009年第5期308-309,共2页 Chinese Journal of Nervous and Mental Diseases
  • 相关文献

参考文献12

  • 1杨学军.解读《世界卫生组织中枢神经系统肿瘤分类(2007年)》[J].中国神经精神疾病杂志,2007,33(9):513-517. 被引量:115
  • 2Kleihues P,Burger PC,Scheithaner BW.The new WHO clarification of brain tumonrs[J].Brain Pathoi,1993,3(3):255 -268. 被引量:1
  • 3Morantz RA,Feign I,Ransoho J.Clinical and pathological study of 24 cases of glioearcoms[J].J Neuroeurg,1976,45 (4):398 -408. 被引量:1
  • 4Badie B,Kramar MH,Lau R,et al.Adenoviruw-medlated P53 gene delivery potentiates the radiation-induced growth inhibition of experimental brain tumors[J].J Neurol,1998,37(3):217 -222. 被引量:1
  • 5Dwyer KW,Naul LG,Hise JH.Glioearcoma:MR features[J].J Comput Assist Tomogr,1996,20(5):719 -723. 被引量:1
  • 6Meis JM,Martz KL,Nelson JS.Mixed glioblastoma muhiforme and sarcoma.A clinicopathologic study of 26 radiation therapy ontology group cases[J].Cancer,1991,67(9):2342 -2349. 被引量:1
  • 7Nitta H Hayase H,Moriyama Y,et al.Giiosarcoma of theposteriot enmial fceea:MRI findings[J].Neuroradiology,i993,35(4):279-280. 被引量:1
  • 8Pakos EE,Goussia AC,Zhna VP,et al.Multl-focal gliosarconm:a caae report and review of the literature[J].J Neurooncol,2005,74 (3):301 -304. 被引量:1
  • 9lutterbach J,Cuttenberger R,Pagenstecherr A.Gliosarcomaa:a clinieal study[J].Radiother 0ncol,2001,61 (1):57 -64. 被引量:1
  • 10张蕾莉,崔世民,徐惠芳,刘梅丽,靳松,闫世鑫,戴伟英,高满.颅内胶质肉瘤的CT与MRI表现[J].中华放射学杂志,2001,35(5):359-361. 被引量:15

二级参考文献15

  • 1秦进喜,孔繁明.10例胶质肉瘤临床病理和免疫组织化学观察[J].中华病理学杂志,1996,25(4):250-250. 被引量:4
  • 2赵兰,卢德宏,徐庆中,杨虹.胶质肉瘤的组织病理学和免疫组织化学的研究[J].中华病理学杂志,1996,25(1):10-12. 被引量:9
  • 3Legha SS.Tamoxifen in the treatment of breast cancer.Ann Intern Med,1988,109(3):219. 被引量:1
  • 4Couldwell WT,Weiss MH,Degiorgio CM,et al.Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high dose tamoxifen.Neurosurgery,1993,32 (3):485. 被引量:1
  • 5Ben Arush MW,Postovsky S,Goldsher D,et al.Clinical and radiographic response in three children with recurrent cerebral malignant tumors with high-dose tamoxifen.Pediatr Hematol Oncol,1999,16(3):245. 被引量:1
  • 6Pollack IF,Kawecki S,Lazo LS.Blocking of glioma proliferation in vitro and in vivo and potentiating the effects of BCNU and cisplatin:UCN-01,a selective protein kinase C inhibitor.J Neurosurg,1996,84(6):1024. 被引量:1
  • 7Ramachandran C,Khatib Z,Petkarou A,et al.Tamoxifen modulation of etoposide cytotoxicity involves inhibition of protein kinase C activity and insulin-like grwoth factor Ⅱ expression in brain tumor cells.J Neurooncol,2004,67 (1-2):19. 被引量:1
  • 8Brat DJ,Scheithauer BW,Fuller GN,et al.Newly codified glial neoplasms of the 2007 WHO classification of tumours of the central nervous system:angiocentric glioma,pilomyxoid astrocytoma and pituicytoma.Brain Pathol,2007,17(3):319. 被引量:1
  • 9Kleihues P,Burger PC,Scheithauer BW.The new WHO classification of brain tumours.Brain Pathol,1993,3 (3):255. 被引量:1
  • 10Daumas-Duport C,Varlet P.Dysembryoplastic neuroepithelial tumors.Rev Neurol (Paris),2003,159(6 -7Ptl):622. 被引量:1

共引文献131

同被引文献39

  • 1张建,赖睿佳,何亚文.胶质肉瘤10例临床分析[J].广东医学,1995,16(9):577-578. 被引量:4
  • 2李南云,钱源澄,马恒辉,郑晓刚,陆珍凤,严小娟.胶质肉瘤的临床病理研究[J].中华病理学杂志,1996,25(3):129-131. 被引量:13
  • 3Züchner S,Kawohl W,Sellhaus B,et al.A case of gliosarcoma appearing as ischemic stroke.J Neurol Neurosurg Psychiatry,2003,74:364 -366. 被引量:1
  • 4Beaumont TL,Kupsky WJ,Barger GR,et al.Gliosarcoma with multiple extracranial metastases:case report and review of the literature.J Neurooncol,2007,83:39-46. 被引量:1
  • 5Ehrenreich T,Devlin JF.A complex of glioblastoma and spindlecell sarcoma with pulmonary metastasis.Arch Pathol,1958,66:536-549. 被引量:1
  • 6Witwer BP,Salamat MS,Resnick DK.Gliosarcoma metastatic to the cervical spinal cord:case report and review of the literature.Surg Neurol,2000,54:373-378. 被引量:1
  • 7Wharton SB,Whittle IR,Collie DA,et al.Gliosarcoma with areas of primitive neuroepithelial differentiation and extracranial metastasis.Clin Neuropathol,2001,20:212-218. 被引量:1
  • 8Han SJ,Yang I,Tihan T,et al.Primary gliosarcoma:key clinical and pathologic distinctions from glioblastoma with implications as a unique oncologic entity.J Neuroonco1,2009,93:212-220. 被引量:1
  • 9Louis DN,Ohgaki H,Wiestler OD,et al.The 2007 WHO classification of tumours of the central nervous system.Acta Neuropathol,2007,114:97-109. 被引量:1
  • 10Salvati M,Carolil E,Raco A,et al.Gliosarcomas:analysis of 11 cases do two subtypes exist? J Neurooncol,2005,74:59-63. 被引量:1

引证文献3

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部