摘要
目的探讨Asperger综合征（AS）儿童共患精神分裂症的比例并对相关因素进行分析，为AS的评估和干预提供可能的指导。方法对采用DSM-IV标准确诊为AS且定期复诊（至少每6个月1次或每年2次），并有详细完整记录的139名5～15岁患者进行回顾性调查分析。结果有5例AS患者共患精神分裂症，均为男性，年龄为10—14岁。共患精神分裂症组患者平均言语智商（VIQ）、操作智商（PIQ）、总智商（FIQ）分别为（96．3±15．0）分、（81．7±6．4）分、（88．3±8．0）分，非共患组VIQ、PIQ、FIQ分别为（91．8±20．8）分、（88．6±17．7）分、（89．5±18．9）分，2组间差异无显著性（P〉0．01）；共患组比非共患组有更高比例的一、二级亲属精神病家族史（P〈0．01）。结论AS患者共患精神分裂症的比率较高，在临床治疗中应予重视。
Objective To study the rate of children with Asperger syndrome （AS） comorbid with schizo- phrenia and to analyse the related factors. Methods 139 detailed case records of patient （ according to DSM-IV criteria ） aged 5.4 - 15.2 were selected for review, and the patients had received comprehensive evaluations and were followed periodically at our center（ at least semiannually or twice per year）. Results There were five male individuals had a diagnosis of schizophrenia when they aged 10.1 - 14.0. The average VIQ,PIQ,FIQ of individuals comorbid with schizophrenia were respectively 96.3 ± 15. 0, 81.7 ± 6.4,88.3 ± 8.0 and outcomes of the rest individuals were respectively 91.8 ± 20.8,88.6 ± 17.7,89.5 ± 18.9, there were no significant statistically difference between two groups（P〉0.01 ）. The frequency of psychiatric history of the first or the second family in the individuals comorbid with schizophrenia were higher than that in the individuals without schizophrenia （P 〈 0.01 ）. Conclusion It appears that the frequency of schizophrenia among AS patients is high ,which should pay attention to.
出处
《中华行为医学与脑科学杂志》
CAS
CSCD
北大核心
2009年第4期317-318,共2页
Chinese Journal of Behavioral Medicine and Brain Science
