摘要
目的观察肠鸣音与胃肠运动的相关性。方法2组健康成人志愿者,每组6例,分别注射甲硫酸新斯的明和山莨菪碱注射液。结果注射新斯的明后肠鸣音有逐步增多的趋势,第3、5、6、7、8时段的肠鸣音脉冲次数与注射前相比,差异有显著性(P<0.05或0.01);注射山莨菪碱后肠鸣音明显减少,第2、3、4、5、6、7、8时段的肠鸣音脉冲次数与注射前相比,差异有显著性(P<0.05或0.01)。结论肌肉注射促进胃肠运动药物可随着药效作用时间而同步出现肠鸣音增多,而抑制胃肠运动药物则出现肠鸣音同步减少,从药效学的角度证明了肠鸣音与胃肠运动具有相关性。
Objective To explore the correlation between bowel sound and gastrointestinal movement. Methods 12 healthy adult volunteers were divided into two groups, The promotion group （n=6） were injected intramuscularly with neostigmine methylsulfate, and the inhibition group （n=6） with anisodamine hydrobromide. Results The times of bowel sound increased gradually after neostigmine methylsulfate injection, there were significant differences in the times of bowel sound between pre-injection and the 3^rd, 5^th, 6^th, 7^th, 8^th time interval after injection （P〈0.05 or 0.01）; the times of bowel sound decreased gradually ＇after anisodamine hydrobromide injection, there were significant differences in the times of bowel sound between pre-injection and the 2^rd, 3^rd, 5^th, 6^th, 7^th, 8^th time interval after injection （P〈0.05 or 0.01）. Conclusion The times of bowel sound increase gradually after intramuscular injection of promoting gastrointestinal movement medicine and decrease gradually with inhibiting gastrointestinal movement medicine, which proves the correlation between bowel sound and gastrointestinal movement from the angle of pharmacodynamics.
出处
《福建中医学院学报》
2009年第3期41-43,共3页
Journal of Fujian College of Traditional Chinese Medicine
基金
国家973计划(2005CB523308)
卫生部科学基金(WKJ2005-2-004)
福建省卫生厅重点课题(2002-405)
关键词
肠鸣音
胃肠运动
相关性
新斯的明
山莨菪碱
bowel sound
gastrointestinal movement
correlation
neostigmine methylsulfate
anisodamine hydrobromide
