摘要
目的探讨羟喜树碱联合卡介苗并交替膀胱灌注预防膀胱癌术后复发的疗效。方法将门诊及住院的首发膀胱癌术后患者34例用羟喜树碱联合卡介苗并交替进行膀胱灌注。结果所选择病例均为T1或T2期开放手术或TURBT术后患者,其中5例于术后8～12个月复发(14.7%),无并发症发生。结论羟喜树碱联合卡介苗并交替膀胱腔内灌注预防浅表膀胱癌术后复发疗效肯定,毒副反应小,有一定的临床实用价值。
Objective To investigate the curative effect on recrudescence of bladder cancer operation by combining HCPT and BCG vaccine. Methods Bladder irrigation were given for 34 patients either outpatient or in hospital by combining HCPT and BCG vaccine. All the chosen cases were T1, T2 stage of open surgery, or patients after TURBT operation. In order to observe the recrudescence, urine routine and cystoscopy are needed every 3 months in the first year after operation. Results Follow ups of all the patients for 18 - 36 months,with an average of 20 months. Five cases had the recrudescence in 8 - 12 months after the operation（ 14.7% of the total）, without complications. Conclusion The curative effect on recrudescence of bladder cancer operation by combining HCPT and BCG vaccine is positive, with minor toxic and side effects. This method has a clinical application value.
出处
《中国现代医生》
2009年第15期31-32,共2页
China Modern Doctor
关键词
膀胱癌
羟喜树碱
卡介苗
膀胱灌注
复发
Bladder cancer
Hydroxycamptothecine （HCPT）
Bacillus Calmette-Guerin vaccine （BCG vaccine）
Irrigation of bladder
Recrudescence
