摘要
人类白细胞介素-24基因（hIL-24）是一个既抑制肿瘤生长又调节免疫系统功能的细胞因子类的抑癌基因，可以特异性地抑制多种肿瘤细胞生长并诱导其凋亡，同时与其他基因治疗、放疗、化疗、细胞因子治疗等方式联合应用有抗肿瘤协同效应，能显著提高杀伤肿瘤的效果，为肿瘤治疗的研究提供了新的思路。
The human interleukin-24 gene （hlL-24）,also referred to as melanoma differentiation associated gene-7 （MDA-7）, is a novel cancer-selective apoptosis-inducing cytokine gene with broad- spectrum antitumor activity. Multiple data have demonstrated that treatment of tumors with a combination of IL-24 and other strategies such as drug therapy, radiation, dual gene therapy and so on, caused synergistic antitumor effects. These results will provide a impetus for further combination therapy in various tumors.
出处
《肿瘤研究与临床》
CAS
2009年第5期358-360,共3页
Cancer Research and Clinic
