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凝血酶与肺纤维化

Thrombin and pulmonary fibrosis
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摘要 凝血酶不仅在凝血过程中起主导作用，还可以促进细胞增殖，使细胞发生表型变化及参与炎症反应，在肺纤维化形成过程中起重要作用。现就凝血酶及其受体的特性、凝血酶与肺纤维化的关系及其作用机制作一综述。 Thrombin not only has major effect in blood clotting,but also promotes cell proliferation to eause the cell diversified in phenotype, and participates in inflammatory reaetion. So thrombin has a significant role in the formation of pulmonary fibrosis. This article reviews the charaeteristies of thrombin and its receptor,the relationship of thrombin with pulmonary fibrosis and its mechanism.
作者 李晓娟 蔡志刚 张涛
机构地区 河北医科大学第二医院呼吸内科
出处 《国际呼吸杂志》 2009年第10期613-615,共3页 International Journal of Respiration
关键词 凝血酶 肺纤维化 生物学 受体 Thrombin Puhnonary fibrosis
分类号 R563 [医药卫生—呼吸系统]
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参考文献16

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二级参考文献11

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共引文献15

国际呼吸杂志
2009年 第10期

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