摘要
高血压病是心、脑、血管疾病的主要危险因素,如不加以治疗可导致严重的后果。尽管目前有多种类型的抗高血压药物,但相当多的高血压病患者血压未能得到有效的控制,所以理想的抗高血压药物不但要有效,而且副作用的发生率也要低。血管紧张素Ⅱ(AngⅡ)受体(ATI)拮抗剂的出现代表高血压病治疗的一个重要进展,使在受体水平拮抗循环和局部的Angn作用成为当前抗高血压药物治疗的新观念和新方法。缬沙坦(Valsartan),是口服非肽类高效、长效、低毒药物,具高度特异性的选择性AT:拮抗剂。
Hypertension is the key risk factor of heart, brain and vascular disease. It will induce severe consequence if don＇ t to deal with. Although there are many anti - hypertension drugs, however considerable patients have not been eontroUed effectively. The ideal anti - hypertension drug should be not only effective but also low side effect. The appearanee of Angiotensin Ⅱ （AngⅡ） receptor（ATI） antagon represent an important progress in the treatment of hypertensive disease. To rivalry circular and local Ang Ⅱ has became a new concept and new method in the drag treatment of anti - hypertension now. Valsartan is a kind of orally, not poptide, high performance, prolonged action, low toxin, high degree of specific and selective AT antagon.
出处
《黑龙江医学》
2009年第5期352-353,共2页
Heilongjiang Medical Journal
关键词
缬沙坦
高血压
药理
Valsartan
Hypertension
Pharmacology
