摘要
目的:对比研究18F-FDGPET-CT全身显像与99mTc-MDP全身骨骼显像对肺癌骨转移诊断的价值。方法:回顾性研究49例病理证实为肺癌的患者,男28例,女21例,平均年龄(58.9±10.8)岁,所有患者均于10天内分别行18F-FDGPET-CT全身显像与99mTc-MDP全身骨显像,最终骨转移癌诊断结果由手术病理、MR检查或临床随访半年以上病灶范围扩大或加重证实。结果:49例患者18F-FDGPET-CT与99mTc-MDP全身显像共检出异常病灶259处,其中被证实为转移灶228处,31处为良性病灶。18F-FDGPET-CT和99mTc-MDPSPECT诊断骨转移癌的灵敏度为90.8%和56.6%,特异性为93.5%和45.2%,准确性为91.1%和55.2%。结论:18F-FDGPET-CT全身显像对肺癌骨转移诊断的灵敏度、特异性及准确性均高于99mTc-MDP全身骨显像。
Objective： To compare the diagnostic value of ^18F-FDG PET-CT and ^99mTc-MDP bone scintigraphy for the detection of bone metastases in patients with lung cancer. Methods： We examined 49 patients, 28 men, 21 women with lung cancer, mean age （58.9±10.8）years. All patients underwent both whole-body ISF-FDG PET-CT and ^99mTc-MDP bone scintigraphy within 10 days. Bone metastases were verified either by pathological results or MR findings or follow-up more than half a year. Results： Bone metastases were confirmed in 228 of the 259 foci. The sensitivity for bone metastases using ^18F-FDG PET-CT and ^99mTc-MDP as 90.8% and 56.6% respectively, the specificity was 93.5% and 45.2% respectively. The accuracy was 91.1% and 55.2% respectively. Conclusion： The specificity and the overall accuracy of ^18F-FDG PET-CT for the diagnosis of bone metastases in patients with lung cancer are higher than those of ^99mTc-MDP bone scintigraphy.
出处
《中国临床医学影像杂志》
CAS
北大核心
2009年第5期323-326,330,共5页
Journal of China Clinic Medical Imaging
