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缺氧性肺动脉高压新生儿右心室功能的组织速度多普勒超声研究 被引量:4

Research on right ventricular function in neonates with hypoxic-induced pulmonary hypertension by tissue velocity Doppler imaging technology
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摘要 目的探讨组织速度多普勒成像(TVI)技术评价缺氧性肺动脉高压(HPH)新生儿右心室功能的价值。方法35例HPH患儿及28例正常新生儿于生后3d应用超声心动图测量肺动脉收缩压(PASP),用传统超声技术测定右室射血分数(RVEF)值、右心室舒张早期峰值(E峰)、舒张晚期峰值(A峰)、E/A值,同时以TVI技术测量三尖瓣环指标(收缩期波Sa、舒张早期波Ea、舒张晚期波Aa、Ea/Aa值)。结果HPH组三尖瓣环Sa、Ea、Ea/Aa及RVEF值较对照组减低(t=2.67~4.69,P均<0.01)。HPH组的右心室E/A值较对照组减低,但差异无统计学意义。HPH组的三尖瓣环Sa与RVEF值呈正相关(r=0.451,P<0.05)。结论HPH新生儿的右心室舒张、收缩功能减低,TVI技术与传统超声技术结合能更敏感地发现右心室功能变化。 Objective To investigate the roles of tissue velocity Doppler imaging (TVI) technology in assessing fight ventrieular function in neonates with hypoxia-indueed pulmonary hypertension (HPH). Methods Thirty-five (35) three-day-old neonates of HPH group and 28 healthy neonates of control group were performed echocardiographic examinations to measure the pulmonary artery systolic pressure (PASP) , and conventional ultrasound technology to get their right ventricular ejection fraction (RVEF), early diastolic peak (peak E) , late diastolic peak (peak A) and E/A ratio, indicator of the tricuspid valve in right ventricle (including systolic wave-Sa, early diastolic wave-Ea, and late diastolic wave-Aa) were also determined using TVI technology. Results Compared with the control group, the value of Sa, Ea of the tricuspid valve, Ea/Aa ratio and the RVEF were decreased in HPH group (all P 〈 0.01). The E/A ratio of right ventricle were also decreased, but there was no statistical significance between the two groups. Sa value of the tricuspid valve was positively correlated with that of the RVEF in HPH group (r = 0.451, P 〈 0.05). Conclusions Neonatal pulmonary artery hypertension can lead to disorders of the fight ventricular function. TVI technology combined with conventional ultrasound technology can make the evaluation of systolic and diastolic function of fight ventricle more sensitive in newborns with HPH.
出处 《临床儿科杂志》 CAS CSCD 北大核心 2009年第5期484-487,共4页 Journal of Clinical Pediatrics
关键词 缺氧性肺动脉高压 右心室功能 新生儿 组织速度多普勒成像 hypoxia-induced pulmonary hypertension right ventricular function newborn tissue velocity Doppler imaging technology
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同被引文献37

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