摘要
目的:研究CNP在人乳牙根生理性吸收过程中的mRNA表达及作用。方法:运用原位杂交方法检测人乳牙根生理性吸收过程中CNP的mRNA表达。结果:生理性吸收期乳牙的破牙细胞、牙髓成纤维细胞及成牙本质细胞CNP表达阳性。结论:人乳牙牙根生理性吸收过程中CNP可能促进破牙细胞的分化和活性,可能对乳恒牙替换起到一定的促进作用。
Objective：To investigate the function and the expression of CNP mRNA during physiological resorption of human primary teeth, nethod：CNP was observed to express in physiological resorption of human primary teeth root by immunohistochemistry and in situ hybridization. Result：CNP positive signals were observed in odontoclast,pulp fibroblast and odontoblast in primary teeth. Conclusion：CNP might participate in odontoclastogenesis and activation of physiological root resorption during the stage of the physiological root resorption and involve in the replacement of primary and permanent teeth.
出处
《临床口腔医学杂志》
2009年第5期261-263,共3页
Journal of Clinical Stomatology
基金
黑龙江省教育厅科学技术研究资助项目(11521115)
哈尔滨医科大学第一临床医学院科研基金项目
关键词
乳牙根生理性吸收
C型利钠利尿肽
破牙细胞
physiological resorption of human primary teeth
C-type natriuretic peptide
odontoclast
