摘要
目的探讨流感病毒快速检测方法在流感样病例诊断中的意义。方法采用流感病毒快速检测方法和(或)MDCK细胞培养法对228例流感样病例进行病原学检测,并分析流感样病例的临床特点。结果流感病毒快速检测方法的阳性检出率为22.6%,MDCK细胞培养法的阳性检出率为15.4%;流感病毒快速检测方法的敏感性为55.6%,特异性为75.9%,阴性预测值为94.0%,与细胞培养方法的一致率为73.9%。结论流感病毒快速检测方法特异性高、阴性预测值高、与细胞培养方法的一致率高,在流感流行季节对于流感的快速诊断和筛查,有一定临床意义。
Objective To investigate the application of point-of-care rapid influenza test in the diagnosis of patients with influenza-like illness. Methods Point-of-care rapid influenza test and/or MDCK cell culture were performed in 228 patients with influenza-like illness, and the clinical features were analyzed. Results The positive rate of point-ofcare rapid influenza test was 22.6% and the positive rate of MDCK cell culture was 15.4%. The sensitivity, specificity, and negative predictive value of the point-of-care rapid influenza test were 55.6%, 75.9% and 94.0% respectively. And concordance rate with cell culture was 73.9%. Conclusions The point-of-care rapid influenza test has high sensitivity, specificity, negative predictive value and concordance rate with cell culture. In the influenza season, the point-of-care rapid influenza test has definite clinical significance for the rapid diagnosis and screening of influenza.
出处
《北京医学》
CAS
2009年第5期280-283,共4页
Beijing Medical Journal
