摘要
为了探讨直接检测血清离子钙的正常参考值范围以及血清钙测定在血清蛋白异常标本中的变化，用美国NOVA—Nucleus全自动分析仪直接对130例正常人血清离子钙进行了检测，结果，血清实测离子钙正常参考范围为0．97±0．08mmol／L，正常化离子钙为1．25±0．10mmol/L。同时，根据血清总蛋白和白蛋白测定结果，对64例血清蛋白异常病人的总钙和离子钙作分组分析，结果显示，当病人血清白蛋白低于正常范围时，血清总钙明显下降（P＜0．01），而离子钙与正常组比较差异无显著性（P＞0．05）．此外，比较了低白蛋白血症病人血清总钙与离子钙的异常率，表明，在低白蛋白血症病人中，不论是血清总钙浓度还是离子钙浓度均有偏低现象出现，但以总钙偏低为多，两者差异有高度显著性（P＜0．01）。离子钙是在人体血液中能真正发挥生理功能的钙，低白蛋白血症患者常因白蛋白水平降低而致与之结合部分的钙浓度降低，造成总钙水平下降，而离子钙不一定偏低，因此，临床上检测离子钙较之总钙更具有意义．
In order to determine the normal reference value of serum ionized calcium and thechanges of serum ionized calcium in patients with hypoalbuminemia,serum ionized calcium con-centrations of 130 normal people were measured with the NOVA-Nucleus automatic analyzerand the rates of serum ionized calcium and total calcium in 64 patients with hypoalbuminemiawere compared. The results of the normal reference ranges for serum ionized calcium is 0. 97±0. 08 mmol/L and the normalized ionized calcium is 1. 25±0. 10 mmol/L. In patients with hy-poalbuminemia,the total serum calcium was significantly lower than that of the control group(P<0. 01) and there was no significant changes in serum ionized calcium (P>0. 05). The ab-normal rates between the concentrations of total and the ionized calcium were significant (P<0.01). Since serum ionized calcium plays physiological function in the body, determination of ion-ized calcium is more significant than that of the total calcium.
出处
《陕西医学检验》
1998年第1期8-10,共3页
Shaanxi Journal of Medical Laboratory Sciences
