摘要
目的观察胰岛素(诺和灵30R)对2型糖尿病口服降糖药控制不佳并有程度不等慢性并发症患者的疗效。方法68例2型糖尿病患者每天用诺和灵30R24～60U,早晚2次餐前半小时皮下注射,共观察12周。结果治疗前后患者的空腹血糖、餐后2h血糖、糖化血红蛋白均有明显下降(P<0.01),血压、血脂、肝功、肾功、心电图等指标较治疗前有不同程度改善。结论2型糖尿病在口服降糖药不能很好地控制血糖,且在有不同程度的慢性并发症的情况下,应尽早改用胰岛素治疗,使血糖控制在正常或接近正常水平,避免或延缓各种并发症的发生和发展。
Objective To investigate the efficacy of insulin（Novolinmix30） in treatment of patients with type 2 diabetes who had poor responses to oral hypoglycemic agents （OHAs） and chronic complications in varying degrees. Methods 68 type 2 diabetic patients received twice a day regimen of insulin treatment. After achieving a good control for 12 weeks,the doses of Novolinmix30 required were 24-60U one day. Results Compared with baseline, fasting plasma glucose （FPG）, 2 hours postprandial blood glucose （2hPG） and haemoglobin A1c（HbA1c） were significantly decreased（P〈0.01）, blood pressure, tipids, as well as other targets were different degrees of improvement than pre-treat-ment. Conclusion It is necessary to take insulin treatment as early as possibly in type 2 diabetic patients to delay or avoid acute and chronic complications,who took OHAs with poor glycaemic control.
出处
《中国现代医生》
2009年第13期68-69,共2页
China Modern Doctor
关键词
2型糖尿病
胰岛素治疗
Type 2 diabetes mellitus
Insulin treatment
