摘要
目的通过对比研究高度近视患眼，植入虹膜夹持型前房型人工晶状体（Verisyse）手术前后的角膜内皮细胞数以及视功能的变化，以期评价该术式的临床有效性和安全性。方法对高度近视患者16例28只眼行有晶状体眼前房型人工晶状体植入术，监测术后远近视力、屈光度、调节幅度、角膜内皮细胞密度、眼压及眼前节的情况，比较手术前后以上指标的变化。结果随访12～28个月（平均16个月）。（1）患者术后均无明显主观不适感，晶状体位置亦无明显偏心。（2）所有患者裸眼远视力均有所提高，近视力无显著差异，调节幅度较术前提高，差异有统计学意义。术前：（3．18±0．89）D，术后12月：（5．34±0．78）D；P〈0．05。（3）角膜内皮细胞密度：术前：（3275．52±331．16）个／mm^2，术后12月（2889．03＋352．64）个／mm^2；P〉0．05；和角膜内皮细胞变异系数：术前：（0．51±0．05）％，术后12月：（0．53±0．07）％；P〉0．05；术前及术后相比差异无统计学意义。（3）术后12个月平均屈光度为（-0．59±0．28）D。结论虹膜夹持型前房型人工晶状体植入矫正高度近视在术后随访中安全有效，无明显并发症，尤其是角膜内皮细胞数无显著衰减，但更长期的随访监测实属必要。
Objective To evaluate the efficacy and safety of phakic anterior chamber intraocular lens implantation for high myopia.Methods Verisyse implantations were performed on 16patients （28eyes）with high myopia,Visual acuity including far and near sight,accomodative ability,mean counts of endothelium were checked at pre-and post-operation.Results The average follow-up was 16 months（12-28months）.Any complain was not detected and tilting or decentration was not found obviously; Uncorrected visual acuity after operation was betterthan that of before.The mean accommodation was （3.18 ±0.89）D pre-operat ion, and （5.34 ± 0.78）D at 12 months post-operation, the mean accommodation was improved markedly compared with that of pre-operation （ P 〈0.05 ） ; The mean counts of endothelium were 3275.52 ± 331.16/mm^2 preoperatively and 2889.03＋ 352.64/mm^2 12months postoperatively, There was no significant difference betweenthem （P 〉 0.05）.The mean postoperative spherical equivalent was-0.59 ± 0.28D.Conelusion The implantation of phakic anteriorchamber IOL for high myopia is effective,safe and stable without any severe complication at short term following-up.
出处
《中国实用眼科杂志》
CSCD
北大核心
2009年第5期452-455,共4页
Chinese Journal of Practical Ophthalmology
