摘要
苄叉丙酮与芳香胺和芳香醛在０～２５℃和少量浓盐酸催化下能直接进行Ｍａｎｎｉｃｈ反应，生成了相应的Ｍａｎｎｉｃｈ碱（Ⅰ）———５芳基５芳胺基１苯基１戊烯３酮，产率为５４％～９３％，共合成了１４个新化合物．产物的结构经元素分析、１ＨＮＭＲ、ＩＲ和ＭＳ证实．还讨论了反应的适宜条件．
n the presence of small amount of concentrated hydrochloric acid,the Mannich reaction of benzalacetone,aromatic aldehydes and aromatic amines can take place directly at 0～25℃.Fourteen corresponding Mannich bases(Ⅰ),5 aryl 5 arylamino 1 phenyl 1 penten 3 one,were prepared with 54%～93% Yield.All of these Mannich bases(Ⅰ) were new compounds.These target compounds were verified by elemental analyses,IR, 1 HNMR,MS.The reaction conditions were also discused.
出处
《西南师范大学学报（自然科学版）》
CAS
CSCD
北大核心
1998年第3期298-302,共5页
Journal of Southwest China Normal University(Natural Science Edition)
关键词
MANNICH反应
苄叉丙酮
芳香醛
芳香胺
Mannich reaction
Mannich bases
benzalacetone
aromatic aldehydes
aromatic amines
