摘要
为了探讨原发性男性生殖系统恶性淋巴瘤(PMGSL)的临床特点、治疗方法及预后,回顾性分析了30例原发男性生殖系统恶性淋巴瘤临床资料。结果显示,PMGSL占同期恶性淋巴瘤的0.7%,以睾丸恶性淋巴瘤最为常见,占PMGSL的86.67%。治疗方法采用手术、化疗和放疗相结合的综合治疗。全组患者中位生存期(MST)24个月,5年生存率35.2%。PMGSL预后与分期及病理分型有关,晚期病例的预后明显差于早期病例,P<0.05;B细胞性NHL的预后好于T细胞性NHL,P<0.05。初步研究结果提示,PMGSL是罕见的结外淋巴瘤,治疗方法应采用化疗、手术和放疗为主的综合治疗,分期和病理分型是预后的影响因素。
The objective of this study was to explore the clinical characteristics, reasonable mode of treatment and prognostic factors in the patients with primary male genital system lymphoma（PMGSL）. The clinical data of 30 patients with PMGSL treated from 1976 to 2005 were retrospectively reviewed. PMGSL accounted for 0.7% of all non-Hodgkin lymphomas that presented in the corresponding period. It mainly involved testicular lymphoma with a percent of 86.67%. Most patients received comprehensive treatment including surgery, chemotherapy and/or irradiation. The median follow-up of the survival patients was 24 months. The 5-year overall survival rate was 35.2%. An Arbor stage and pathological type were significant prognostic factors for survival.The prognosis of B cell NHL was better than that of T cell NHL （P〈0.05）. In conclusin, PMGSL is a rare entity of extranodal lymphoma. Chemotherapy plays a very important role in comprehensive treatment. The significant prognostic factors for survival are stage and pathological type.
出处
《中华肿瘤防治杂志》
CAS
2009年第6期473-474,共2页
Chinese Journal of Cancer Prevention and Treatment
