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CD4^+CD25^(high)FOXP3^+调节性T细胞与肿瘤的研究进展 被引量:3

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摘要 调节性T细胞(regulatory T cells,Treg)是具有一定免疫抑制功能的T细胞亚群。随着分子生物学技术的不断进步,以及对FOXP3基因功能的明确,近年来对调节性T细胞的认识有了新的界定(即是一群CD4+CD25high FOXP3+regulatory T cell)。其在临床自身免疫性疾病,移植物抗宿主反应以及肿瘤等领域有着重要的作用,尤其是对于肿瘤的发生发展及临床治疗和预后有着重要的意义[1]。本文就CD4+CD25high FOXP3+调节性T细胞与肿瘤的最新研究进展作一简要综述。
出处 《现代肿瘤医学》 CAS 2009年第5期981-984,共4页 Journal of Modern Oncology
基金 安徽省高等学校省级自然科学研究项目(皖科计字[2006]135号)
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同被引文献51

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