摘要
目的观察缺血预处理(IPC)对急性心肌梗死(AMI)的影响。方法63例初发AMI并接受住院治疗的患者,根据梗死前有无心绞痛症状分为IPC组和PC组,比较两组患者的观察指标。结果IPC组小面积心肌梗死发生率高于PC组,而大面积心肌梗死发生率低于PC组,且IPC组比PC组血清CPK峰值低,严重并发症及病死率均减低(P<0.05或P<0.01)。结论IPC具有保护心肌、缩小梗死范围、改善初梗患者近期预后的作用。
Objective To outline the clinical outcomes of ischemic preconditioning （IPC） on acute myocardial infarction （AMI）. Methods 63 hospitalized patients with initial AMI were divided into two groups： group IPC with angina before AMI, no ischemic preconditioning group （group PC） without angina. The recorded indexes between the groups were compared. Results The incidence of small size infarction was higher in group IPC than that in group PC, The peak value of CPK in group IPC was lower than that in group PC. The incidence of serious complications and mortality in group IPC decreased significantly than those in group PC （ P 〈 0.05 or P 〈 0.01）. Conclusion IPC plays a role of protecting myocardium and shrinking the infarction size, and improving short- term prognosis of early AMI.
出处
《右江民族医学院学报》
2009年第2期168-169,共2页
Journal of Youjiang Medical University for Nationalities
关键词
缺血预处理
心肌梗死
预后
ischemic preconditioning
myocardial infarction
prognosis
