摘要
合成了数个新手性双-(三氟甲磺酰)亚胺基二硫代缩酮基硅路易斯酸2～4,并研究了它们对环戊二烯和丙烯酸衍生物11a～11c的Diels-Alder反应的催化活性.结果表明催化剂活性高,环加成反应的产率高达89%～96%,并且获得较高的非对映选择性和中等对映选择性,当催化剂为2b时,反应的对映选择性达到最高,为48%ee.
A few of new chiral bis-（trifluoromethylsulfonyl）imidyl dithioketal silanes 2-4 were prepared, and used as catalysts for Diels-Alder reactions of cyclopentadiene with acrylic acid derivatives 11a-11c. The results showed that these catalysts were very efficient by high yields （89%-96%）, good diastereoselec- tivity and moderate enantioselectivity of the catalyzed cyclic additions. The ee values of the cyclic addition reactions were up to 48% when compound 2b was used as catalyst.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2009年第4期653-657,共5页
Chinese Journal of Organic Chemistry
基金
教育部留学回国人员科研启动基金(No.[2007]1108)
湖南省自然科学基金(No.06JJ50016)
湖南省教育厅(No.07C288)
湖南科技大学博士启动基金(No.E55105)资助项目.
