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慢性乙型肝炎患儿外周血B淋巴细胞亚群的临床意义分析 被引量:2

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摘要 目的:探讨慢性乙型肝炎(CHB)患儿外周血B淋巴细胞各亚群的特点及其与CHB的关系。方法:采用流式细胞技术对CHB患儿33例和正常儿童15例外周血B细胞、CD5+B细胞(CD5+,CD19+)及CD5-B细胞(CD5-,CD19+)亚群进行检测,并结合血清转氨酶(ALT)和病毒载量水平进行临床分析。结果:CHB患儿外周血B细胞、CD5+B细胞及CD5-B细胞亚群与正常儿童比较显著升高,差异显著(P<0.05)。结论:CHB病程中有特异性体液免疫反应发生。
出处 《人民军医》 2009年第5期313-313,331,共2页 People's Military Surgeon
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  • 1Baumgarth N, Herman OC,Jager GC,et al. B- 1 and B--2 cell-derived immunoglobulin M antibody are nonredundant components of the protective response to influenza virus infection[J]. J Exp Med 2000,192(2) :271. 被引量:1
  • 2Martin F, Oliver AM, Kearney JF. Marginal zone and B1 B cells unitein the early response against T independent blood-borne particulate antigens[J]. Immunity, 2001,14 (5) : 617. 被引量:1
  • 3Zuckerman E, Kessel A, Slobodin G , et al. Antiviral treatment down regulate speripheral B-cell CD8 lexpression and CD5 expansion inehroniche patitis Cvirus infection[J].J Virol,2003,77(19) : 10 432. 被引量:1
  • 4Toubi E, Ke_ssel A, Peri R, Shrnuel Z,et al. Enhanced apoptosis of peripheral CD5 negative B lymphocytes from chronically hepatitis C virus-infected patients:Reversal after antiviral treatment[J]. J Virol, 2004,78(20) ; 11 379. 被引量:1

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  • 1徐志强,张鸿飞,杨晓晋,杨斌,王福生.小儿慢性乙型肝炎外周血T细胞亚群和临床病理关系的研究[J].中华实验和临床病毒学杂志,2004,18(2):142-144. 被引量:15
  • 2田瑛,邱志峰,李太生.慢性乙型肝炎患者和乙型肝炎病毒携带者外周血T细胞亚群的变化和意义[J].中华医学杂志,2005,85(47):3354-3358. 被引量:64
  • 3杨淑艳.2型糖尿病患者T淋巴细胞亚群测定及意义[J].白求恩军医学院学报,2007,5(4):234-235. 被引量:7
  • 4FeiGZ, Sylvan SP, YaoGB, et al Quantitativemonitoring ofserumhepatitisB virusDNA and blood lymphocyte subsetsduring combinedprednisalone and interferon -alpha therapy in patients with chronichepatitisB. JViralHepat, 1999, 6:219 - 227. 被引量:1
  • 5Baumgarth N, Herman OC, Jager GC, et al. B - I and B - 2 cell - de - rived immunoglobulin M antibody are nonredundant components ofthe protective re- sponse to influenza virus infection [J]. J Exp Med2000, 192 (2) : 271. 被引量:1
  • 6Martin F, Oliver AM, Kearney JF · Marginal zone and BI B ceUsunitein the early response against T - independent blood - borne particu - late antigens [ J ]. Immunity, 2001, 14 (5): 617. 被引量:1
  • 7Toubi E, Kessel A, Peri R, Shmuel Z, et al. Enhanced apoptosis ofperipheral CD5 - negative B lymphocytes from chronically hepatitis Cvirus - infected patients : Reversal after antiviral treatment [J] .J Virol, 2004, 78 (20) : 11 379. 被引量:1
  • 8林小马,徐蕾.非重症初治涂阴肺结核病人不同化疗方案的效果比较[C].中华医学会2008年全国结核病学术会议论文汇编,2008. 被引量:1
  • 9GARCIA SUAREZ J,KRSNIK I,REYES E,et al. Elderly haematologi- cal patients with chemotherapy-induced febrile neutropenia have similar rates of infection and outcome to younger adults: a prosl~.ctive study of risk-adapted therapy [J]. Br J Haematol,2003,120 (2): 209-216. 被引量:1
  • 10ROWLAND JONESSLTimeline:AIDS pathogenesis:what have two decades of HIV research taught us [J].Nature Renews Immunolog, 2013,3(4) : 343-348. 被引量:1

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