摘要
为了解在生活环境中接触青石棉２０～３０年后患肺癌和间皮瘤的危险，采用回顾队列调查方法，对１６１０名在环境接中触青石棉的农民进行追踪，以无石棉污染地区的７６４６名农民作对照。９年期间，肺癌和间皮瘤的死亡率分别为４３．７５／１０万，３６．４６／１０万。肺癌的相对危险度为５．６７，间皮瘤的ＲＲ为１８２．３（Ｐ＜０．０１），提示青石棉与肺癌和间皮瘤之间存在很强的病因学联系。
To assess the risk of lung cancer and mesothelioma after environmental exposure to crocidolite for 2030 years,a retrospective cohort study was carried out in farmers who had been exposed to crocidolite in environment.1610 subjects were followed up for 9 years(Jan.1,1987 Dec.31,1995).The control group consisted of 7646 farmers who resided in the noncrocidolite pollution rural area in the same province. The results showed that the annual mortality rate was 43.75 per 100 000 population for lung cancer,and 36.46 per 100 000 for mesothelioma.Significantly high risks of lung cancer (RR 5.67) and mesothelioma (RR 182.3) were noted.These results demonstrate a strong causal association between lung cancer,mesothelioma and exposure to crocidolite.
出处
《华西医科大学学报》
CSCD
1998年第1期63-65,共3页
Journal of West China University of Medical Sciences
基金
卫生部科研基金
关键词
青石棉
间皮瘤
肺肿瘤
农民
Crocidolite Lung cancer Mesothelioma
