摘要
目的:系统评价黄芪注射液治疗2型糖尿病的疗效及安全性。方法:检索黄芪注射液治疗2型糖尿病随机对照试验文献,选择合格研究,应用Jadad评分法进行质量评价,运用异质性检验、Meta-分析、漏斗图分析、敏感性分析统计相关数据。结果:4项研究符合纳入标准,Jadad评分均为1分,属低质量文献。黄芪注射液治疗2型糖尿病总有效率比较的合并RR(99%CI)为1.58(1.20,2.09)。结论:Meta-分析结果提示,黄芪注射液治疗2型糖尿病有效、安全。由于纳入研究质量低、统计结果不稳定等因素影响,降低了上述结果的可靠性、真实性,目前证明黄芪注射液治疗2型糖尿病安全有效的证据尚不够十分充分。
Objective： To evaluate systematically the effectiveness and safety of treatment of type 2 diabetes with huangqi injection. Method： Reviewing the literatures of random case control test on type 2 diabetes treatment with huangqi injection selecting eligible research,taking quality assessment with Jadad appraisement, analyzing related data with heterogeneity test, Meta -analysis, funnel plots, sensitivity analysis methods. Result： 4 research issues were in accordance with these criteria and either was 1 by Jadad assessment and low quality. Overall effective rate comparison RR（99% CI） of huangqi injection according to symptoms to treat type 2 diabetes equaled 1.58 （1.20,2.09）. Conclusion： Meta- analysis show that modified huangqi injection according to symptoms diabetes is safe and effective for type 2 diabetes. The factors such as low quality eligible studies reduced the reliability and the validity. The evidence is not very abundant to prove the safety and the availability of treatment of type 2 diabetes with huangqi injection.
出处
《辽宁中医杂志》
CAS
北大核心
2008年第12期1798-1800,共3页
Liaoning Journal of Traditional Chinese Medicine
基金
山东省中医管理局资助课题(2005-114)
关键词
2型糖尿病
黄芪注射液
随机对照试验
系统评价
Type 2 diabetes
Huangqi injection
Randomized controlled trial
Systematic review
