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苯扎氯铵进行膀胱冲洗对导尿管相关下尿路感染的防治 被引量:9

Preventive effect of bladder irrigation with benzalkonium chloride on catheter-related inferior urethral infection
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摘要 目的:探讨使用苯扎氯铵溶液进行膀胱冲洗对长期留置尿管患者下尿路感染的防治效果。方法:30例需要留置尿管超过3d的患者,按住院号单双号分为对照组和观察组,分别采用0.02%呋喃西林溶液和0.0025%苯扎氯铵溶液进行膀胱冲洗,在不同时间点留取中段尿标本进行尿常规及细菌学检测。结果:膀胱冲洗后第5、9天对照组尿白细胞计数明显高于观察组,对照组尿液细菌培养的阳性率明显高于观察组(P<0.01)。结论:用苯扎氯铵溶液进行膀胱冲洗,患者表现出较好的耐受性,能够有效预防和治疗与留置尿管相关的下尿路感染。 Objective: To investigate the preventive effect of bladder irrigation with benzalkonium chloride on catheter-related inferior urethral infection in patients with urethral catheter. Methods: Thirty patients with urethral catheter for more than 3 days were assigned to either control group or observation group according to their admission number. Patients in control group were irrigated with 0.02% nitrofurazone while those in observation group were irrigated with 0. 002 5% benzalkonium chloride. Urine bacterial culture and routine urine test were used to detect the bacteria at different time points. Results: Five and nine days after bladder irrigation, the number of white blood cells in urine was significantly decreased in the observation group. The positive rate of urine bacterial culture was higher in the control group than in the observation group (P 〈 0.01 ). Conclusion: Bladder irrigation with benzalkonium chloride is tolerable and can prevent and alleviate catheter-related lower urinary tract infection.
出处 《军医进修学院学报》 CAS 2009年第2期167-168,共2页 Academic Journal of Pla Postgraduate Medical School
关键词 苯扎氯铵 灌洗 膀胱 泌尿系疾病 护理 benzalkonium chloride irrigation urinary bladder urologic diseases nursing care
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