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手术中乙型肝炎病毒传染源三种监控方法的特点分析 被引量:2

Characteristic Analysis of Three Monitoring Measures of HBV Infective Source in Operations
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摘要 目的选择合理的手术中HBV传染源监控方法。方法通过分析以HBV DNA、HBsAg或HBeAg作为手术中HBV传染源筛查指标的特点,选择合理的监控方法。结果9.0%HBsAg阴性者HBVDNA阳性,传染性在0-10^4ID/ml;73.7%HBsAg阳性者HBV DNA阳性,传染性在0-10^9ID/ml;HBeAg阳性者是HBsAg阳性者中传染性较强部分。HBV经手术传播的感染阈值为10^5 ID/ml。3.20%HBeAg阴性和83.88%HBeAg阳性者可成为传染源,80.77%HBsAg阳性者不能成为传染源。医护人员有效接种乙肝疫苗后的感染阈值为10^8.5 ID/ml,只有3.23%HBeAg阳性者仍能成为传染源。结论HBV DNA监控法、HBsAg监控法和HBeAg监控法均属零危险性的防护标准,以HBeAg监控法更适合国情。 Objective To choose the reasonable monitoring measures of HBV infective source in operations. Methods HBV DNA, HBsAg or HBeAg were selected as the monitoring index of HBV infective sources in operations to seek reasonable solutions. Results Nine percents HBsAg negative patients were HBV DNA positive and the infectivity was 0 - 10^4ID/ml; 73.7 % HBsAg positive patients were HBV DNA positive and the infectivity was 0-10^9ID/ml. HBeAg positive patients had higher infectivity in HBsAg positive patients. HBV infective threshold value was 10^5ID/ml during operations. 3.20% HBeAg negative and 83.88% HBeAg positive patients could be the infective sources. 80. 77% HBsAg positive patients couldn't be the infective sources.Healthcare workers were inoculated against HBV and the HBV infective threshold value was 10^8.5ID/ml during surgical operations. Only 3.23%HBeAg positive carriered still exceed the infective threshold value. Conclusion The measures of HBV DNA, HBsAg or HBeAg as a monito-ring index of HBV in{ective source during operations were all zero risk precautionary standard.Moniting index by HBeAg was more suitable for the current condition of our country.
机构地区 解放军第
出处 《解放军护理杂志》 2009年第7期6-8,共3页 Nursing Journal of Chinese People's Liberation Army
关键词 HBEAG HBV HBSAG 医院感染 HBeAg HBV HBsAg nosocomial infection
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  • 1宫丽莉,王效雷,赖学俊,姜旻岚,孙佩,杨双旺.选择手术中乙型肝炎病毒传染源筛查指标[J].中华医院感染学杂志,2008,18(7):935-937. 被引量:1
  • 2Tarhan M O,Aker A I,Sipahi O R, et al. Accelerated versus classical hepatitis B virus vaccination programs in heath care workers accelerated vs. classical HBV vaccination[J].Med Sci Monit, 2006,12 ( 11 ) : 467-470. 被引量:1
  • 3Pavette P J,Weeratna R D, McCluskie M J, et al. Testing of CpG-optimized protein and DNA vaccines against the hepatitis B virus in chimpanzees for immunogenicity and protection from challenge[J]. Intervirology, 2006,49 (3) : 144-151. 被引量:1
  • 4Gunson R N,Shouval D,Roggendorf M, et al. Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in health care workers (HCWS) : guidelines for prevention , of transmission of HBV and HCV from HCW to patients [J]. J Clin Virol,2003,27(3) :213-230. 被引量:1
  • 5Transley T,Beresford G, Ladas P, et al. Infection of patieflts by bloodborne viruses[J]. Br J Surg,2004,91(4) : 395-399. 被引量:1
  • 6Nystrom P, Wittmann D. Patient to surgeon infections. fact or fiction[J]. Br J Surg,2003,90(11) 11315-1316. 被引量:1
  • 7Jaffray C E,Flint L M. Blood-borne viral diseases and the surgeon[J]. Curr Probl Surg, 2003,40(4) : 195-251. 被引量:1
  • 8Vardas E, Ross M H,Shap G, et al. Viral hepatitis in South African healthcare workers at increased risk Of occupational exposure to blood-borne viruses [J]. J Hosp Infect,2002,50(1) :6-12. 被引量:1

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