摘要
目的:探索嗅三针对痴呆大鼠大脑边缘叶胆碱能系统功能的影响作用。方法:测定大鼠大脑边缘叶乙酰胆碱酯酶(AChE)和胆碱乙酰化酶(ChAT),并测试大鼠记忆能力。结果:迷宫学习记忆能力测试表明,嗅三针组成绩优于模型组(P<0.01);嗅三针组大脑边缘叶乙酰胆碱酯酶(AChE)和胆碱乙酰化酶(ChAT)活性明显高于模型组(P<0.01)。结论:嗅三针可以增强中枢神经胆碱能系统的功能,并且由此对痴呆大鼠产生治疗作用。
Objective：To explore the effect of XIU three needles on cholinergic system in the cerebral marginal lobe of the Alzheimer Disease（AD）rats.Methods：Examing the levels of AChE and ChAT in the cerebral marginal lobe.The leaning-memory ability was tested.Results：Compared with model group,the The leaningmemory ability of XIU three needles group are much better（P〈0.01）;The cerebral marginal lobe AChE and ChAT activities of XIU three needles group were significantly higher than those of model group（P〈0.01）.Conclusion：XIU three needles may reinforce the cholinergic function of central nervous system,thereby to treat the AD rats.
出处
《中国中医基础医学杂志》
CAS
CSCD
北大核心
2009年第3期206-207,共2页
JOURNAL OF BASIC CHINESE MEDICINE
基金
陕西省科学技术研究发展计划项目(2007k13-03(17))
关键词
痴呆
胆碱能系统
嗅三针
XIU three needles
Cholinergic system
Alzheimer Disease
