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步行试验评价阿托伐他汀钙改善心功能衰竭转归初步观察 被引量:6

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摘要 目的:以6min步行试验评价阿托伐他汀钙治疗慢性充血性心力衰竭(CHF)患者后血浆脑利钠肽(BNP)水平的动态变化,探讨阿托伐他汀钙对患者运动耐量及心脏内分泌的病理生理影响。方法:随机入选116例扩张性心肌病伴CHF患者,其中阿托伐他汀钙组59例,另57例为对照组。Bittner方案行6min步行试验。放射免疫法测定BNP。结果:阿托伐他汀钙治疗6个月后,患者症状、运动耐量明显改善,同时血浆BNP水平明显降低。结论:CHF患者接受阿托伐他汀钙治疗后能缓解心衰症状、提高运动耐量,而且显著改善心脏内分泌功能,这种心脏内分泌变化可能有助于心衰预后。
出处 《实用医学杂志》 CAS 北大核心 2009年第7期1130-1132,共3页 The Journal of Practical Medicine
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  • 1Bittner V, Weiner D H, Yusuf S, et al. Prediction of mortality and morbidity with a 6-minute walk test in patients with left ventricular dysfunction [ J ]. JAMA, 1993,270 (14) : 1702-1707. 被引量:1
  • 2Go A S, Lee W Y, Yang J, et al. Statin therapy and risks for death and hopitalization in chronic heart filure [J ]. JAMA, 2006,296 (17): 2105-2111. 被引量:1
  • 3Goldberger J J, Subacius H, Schaechter A, et al. Effects of statin therapy on arrhythmic events and survival in patients with nonischemic dilated cardiomyopathy[ J ]. J Am Coll Cardiol, 2006,48 (6) : 1228-1233. 被引量:1
  • 4Stanek B, Frey B, Hulsmann M, et al . Prognostic evaluation of neurohumoral plasma levels befire and during beta-blocker therapy in advanced left ventricular dysfunction [J]. J Am Coil Cardio1,2001, 38(2) :436-442. 被引量:1
  • 5Kawai K, Hata K, Takaota H, et al. Plasma brain natriuretic peptide as a novel therapeutic indicator in idiopathic dilated cardiomyopathy during Beta-blocker therapy : a potential of hormone guided treatment [J]. Am Heart J,2001,141 (6) : 925-932. 被引量:1
  • 6Dao Q, Krshaswamy P, Kazanergra , et al. Utility of B-type natriuretic peptide in the diagnosis of congestive heart failure in an urgent care setting [ J ].J Am Cardiol, 2001,37 (2):379-385. 被引量:1
  • 7Cheung B M, Kumana C R. Natriuretic peptides relevance in cardiovascular disease [ J ]. JAMA, 1998,280 ( 23 ) : 1983-1984. 被引量:1
  • 8Tsutamoto T, Wada A, Maeda K, et al. Plasma brain natriuretic peptide level as a biochemical marker of morbidity and mortality in patients with asymptomatic or minimally symptomatic left ventricular dysfunction. Comparison with plasma angiotensin II and endothelin-1[J].Eur Heart J, 1999,20(24) : 1799-1807. 被引量:1
  • 9Mozaffarian D, Minami E, Letterer R A, et al. The effect of atorvastatin(10mg) on systemic inflammation in heart failure[J]. Am J Cardiol, 2005,96 (12) : 1699-1704. 被引量:1
  • 10Sola S, Mir M Q, Lerakis S, et al. Atorvastatin improves left ventricular systolic function and serum markers of inflammation in nonischemic heart failure [J ]. J Am Coll Cardiol, 2006,47 (2):332- 337. 被引量:1

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