摘要
目的证实脂蛋白（ａ）是动脉粥样硬化性心脑血管疾病的独立危险因素，探讨心脑血管疾病脂类危险因素中最有价值的危险因子。方法观察诊断明确的冠心病２３６例，脑卒中２４７例，以２４５例健康人和２１８例其他疾病患者为对照，对脂蛋白（ａ）、载脂蛋白Ａ１、载脂蛋白Ｂ、血脂作综合分析。结果冠心病、脑卒中血清脂蛋白（ａ）水平均显著高于健康人组和其它疾病组，并与其它血脂指标均不相关，各指标对心脑血管病的判断价值从高到低依次为：载脂蛋白Ａ１、高密度脂蛋白胆固醇、载脂蛋白Ｂ、脂蛋白（ａ）、低密度脂蛋白胆固醇、总胆固醇、甘油三酯。结论脂蛋白（ａ）是动脉粥样硬化性心脑血管疾病的独立危险因素，脂蛋白（ａ）、载脂蛋白Ａ１、载脂蛋白Ｂ、甘油三酯为心脑血管疾病脂类危险因素中最有价值的危险因子。
Objective To corroborate LP (a) is the independent risk factor of atheroscleorosis and study the most valuable risk factor of blood-lipids in cardiocerebral blood vessel disease.Methods To measure the LP (a), apoA1,apoB and other blood-lipids of 236 cases with coronary-heart disease,247 caeses with cerebral apoplexy,245 cases of normal people and 218 cases of patients with other diseases[WTHX〗Results The LP (a) level of coronary heart disease and cerebral apoplexy is significantly higher than that of the normal gromp and other disease group. The value of blood-lipids in diagnosis of heart-cerebral disease is as follows: apoA1, HDL-C apoB,LP (a), LDL-c, is TC and TG.Conclusion LP (a) is the independent risk factor of cardio-cerebral blood vessel disease related to atheroscleorsis. LP (a), apoA1, apoB and TG are the most valuable of all the risk factors of cardio-cerebral blood vessel diseases.
出处
《济宁医学院学报》
1998年第1期35-38,共4页
Journal of Jining Medical University
关键词
冠心病
脑卒中
脂蛋白(a)
血脂
载脂蛋白
Coronary heart disease
Cerebral apoplexy
Lipoprotein (a)
Blood-lipid
Apolipoprotein
