摘要
目的应用血管回声跟踪技术（echo tracking，ET）对2型糖尿病（T2DM）患者的下肢动脉弹性进行评价，为早期诊断2型糖尿病患者下肢动脉硬化提供量化指标。方法T2DM患者60例，正常对照60例。按年龄分组，应用ET技术评估下肢股总动脉硬化参数，包括压力应变弹性系数（Ep）、硬度指数（B）、顺应性（AC）及增大指数（AI），并对上述参数进行统计学分析。结果T2DM各年龄组股总动脉B、Ep均较正常对照组升高（P〈0．01，P〈0．05），AC均较正常对照组降低（P〈0．01，P〈0．05），AI差别不明显（P均〉0．05）。糖尿病患者40～59岁年龄段弹性参数增幅最大（P均〈0．01）；B、Ep、AC、AI与年龄的相关系数r值分别为0．74、0．76（P均〈0．001）和0．62、0．51（P均〉0．05）。结论T2DM患者股总动脉弹性的下降发生在病变的早期，糖尿病加速动脉硬化在40—59岁年龄段明显提速；8、Ep与年龄相关性明显，AC、AI与年龄相关性不明显。
Objective To study the elastic features of common femoral artery by echo-tracking（ET） technique in type 2 diabetic （T2DM） patients. Method 60 cases of T2DM and 60 cases in control group, were separated into groups with age, ET technique was used to evaluate the common femoral artery modulus, including pressure strain elastic modulus （ Ep）, stiffness parameter （ β）, arterial compliance （ AC）, augment index （AI）. Results Compared with the normal group, in the T2DM group, β and Ep of common femoral artery were significantly higher（P 〈 0.01, P 〈 0.05 ）, and AC was significantly lower（ P 〈 0.05 ）, and the difference in AI was not obvious（ P 〉 0.05 ）. The indexes were most obviouse in 40 to 59-year-old. The correlation parameter of age with β, Ep, AC, AI was 0.74, 0.76 （ P 〈 0.001 ） and 0.62,0.51 （ P 〉 0.05 ）. Conclusion The elasticity declination of common femoral artery in T2DM patients occur in the early stages,the change in 40-59 years old is obvious. β, Ep are apparently age-related indexes,and AC,AI are not.
出处
《中国综合临床》
2009年第4期357-359,共3页
Clinical Medicine of China
基金
广州市医药卫生科技立项项目（2008-YB-044）
关键词
2型糖尿病
超声
股总动脉
血管回声跟踪技术
type 2 diabetes mellitus
Ultrasonography
Common femoral artery
Echo tracking
